Nuclear and Molecular
PET/CT study is an advanced functional imaging using specific radioactive drugs. It is widely used in the field of oncology as well other medical conditions as cardiac viability, neurological disorder, fever of unknown origin and painful orthopedic prosthesis.
The most commonly used compound in PET/CT imaging is FDG, which is analog to glucose. FDG is characterized by high accumulation in malignant cells and used in the early diagnosis and staging of cancer as well as assessment of therapy response and follow-up. FDG compound is also used in other medical conditions.
There are other radioactive compounds used in PET/CT as PSMA, which is used in the assessment of prostate cancer. PSMA can be labeled with Gallium and more recently with Fluorine. Fluorine-PSMA is a cyclotron product compared to Gallium which is laboratory product. Thus Fluorine-PSMA is more pure, highly sensitive and specific and gives a superior images. Alfa scan can provide PSMA in Gallium and Fluorine labeling.
Another compound available in alfa scan is DOTATATE, which is used in cases with neuroendocrine tumors.
Contraindications
- Pregnancy
- Uncontrolled high blood sugar levels
- If treating physician requested
- Contrast CT and the creatinine level is high
Preparations
- Fasting for 6 hours
- Ensure blood glucose level below 180 mg/dL
- Normal creatinine level
The Study
- PET/CT study is a combined exam
- of PET part imaged about 1 hour after administration of the radioactive drugs and a CT scan, in most cases performed after injection of contrast material
After Care
- Good hydration is advised after the exam.
- The amount of radioactive drug is small, however, it is advised to avoid close contact with children and pregnant women for the rest of the exam day.
- If the scan is demanded for nursing mother despite breastfeeding, milk should be collected and discarded for 6 hours after the scan.
Reservation is required for PET/CT studies as the Radioactive drugs should be ordered one day before the test.
PET/CT exam is available in Mohandiseen, Helioples, Maadi and New cairo branches.